Hi, I just sold two S&W model 25's and one 625, probably a mistake. #1 was an older 25 Target, in 45ACP ,scary accurate with SWC reloads. #2 was a 25 Colt, (long colt), and #3 was a 625 3" stainless with an awesome ElPaso Sadlery "Tom Threepersons" holster. A 25 takes 45 ACP with clips or 45 AR (Auto Rim). 45 Colt is not interchangeable with the 45ACP. Ruger made a single action with 2 cylinders one in 45ACP and one in 45 Colt, regards, Mike