With all the choices in calibers and bullet weight available now the only bad choice is to NOT bring enough gun, and to not be capable of shooting accurately the gun you bring. There's no reason to not use enough gun. Even my "little" TC .300 Whisper can fire accurately either a 150 gr. NBT or a 220 gr. SP. The only ass shot that should ever be taken is the Texas Heart Shot. Personally took/made only once & the 50 cal 300 gr launched from my TC Hawken entered just below the "eye" & exited between the shoulder blades, clipping the #2 tine on the right side of a pretty nice 10 point rack. Nice memories while watching a down pour.